RealType® kits allow the simultaneous detection of mutations and variants in human DNA. They are based on Real-time PCR. Just add the DNA from the sample and put it into the thermocycler.
RealType kits are the ideal products to use as a rapid and specific genotyping test. They analyse mutations and variants frequently related to different pathologies or with the response to a treatment.
They are recommended as the first method of genetic study, given that they allow the direct diagnosis of a great number of patients in a fast and economic manner. They are also useful for the screening of asymptomatic population.
Support software for RealType products
BioVisor RT software facilitates the interpretation of the results obtained with RealType products for the study of point mutations through genotyping tests by Real-time PCR.
BioVisor RT imports the fluorescence data from the PCR equipment in real time, analyzes them automatically and issues a report with the result.
The application is validated for the CFX96 (Bio-Rad), QuantStudio 5 (ThermoFisher Scientific), ABI7500 (Life Technologies) and MIC (Biomolecular Systems) instruments.
AOC1 Gene: variantes rs10156191, rs1049742, rs1049793 y rs2052129
Ref.: DDAO-32
APOE (Ɛ2, Ɛ3 y Ɛ4): Cys112Arg y Arg158Cys
Ref.: APOE-32
Gen Factor II: G20210A (gen de la Protrombina)
Ref.: PTRO-32
Gen Factor V: Arg506Gln
Ref.: FVLD-32
Genes Factor V y Factor II: trombofilia Arg506Gln (FV Leiden) y G20210A (gen de la Protrombina)
Ref.: FVPT-32
Gen Factor XII: variante C46T
Ref.: FXII-32
Gen Factor XIII A: variante VaI34Leu (rs5985)
Ref.: FC13-32
Gen HFE: Hemocromatosis Cys282Tyr, His63Asp y Ser65Cys
Ref.: HECR-32
Gen IL28B: rs12979860 y rs8099917
Ref.: IL28-32
Gen MCM6: variantes 13910*T y 22018*A
Ref.: LACT-32
Gen MTHFR: A1298C y C677T
Ref.: MTHF-32
Gen SERPINA-1: Glu342Lys, Val213Ala y Glu264Val
Ref.: AIAT-32