RealType® kits allow the simultaneous detection of mutations and polymorphisms in the human DNA. They are based on Real-Time PCR. They're based on the real time PCR. Just add the sample DNA and put it into the thermocycler. .
RealType kits are the ideal products to use for a rapid and specific genotyping test. They analyse mutations and polymorphisms most frequently related to different pathologies or response to a treatment..
They are recommended as first method of genetic study, given that they allow to directly diagnose a great number of patients in a rapid and economic manner. They are also useful for the screening of asymptomatic population..
The BioVisor RealType software facilitates the interpretation of the results obtained with RealType products for the study of point mutations through genotyping tests by real-time PCR.
The BioVisor RealType imports the fluorescence data from the PCR equipment in real time, analyzes them automatically and issues a report with the result.
The application is validated for the CFX96 (Bio-Rad), ABI7500 (Life Technologies) and MIC (Biomolecular Systems) equipments.
Gen SERPINA-1: Glu342Lys, Val213Ala y Glu264Val
Ref.: AIAT-10, AIAT-20, AIAT-50
Gen APOE (Ɛ2, Ɛ3 y Ɛ4): Cys112Arg y Arg158Cys
Ref.: APOE-10, APOE-20, APOE-50
Genes Factor V y Factor II: trombofilia (Arg506Gln (FV Leiden) y G20210A (gen de la Protrombina)
Ref.: FVPT-10, FVPT-20, FVPT-50
Gen HFE: Hemocromatosis Cys282Tyr, His63Asp y Ser65Cys
Ref.: HECR-10, HECR-20, HECR-50
Gen MTHFR: A1298C y C677T
Ref.: MTHF-10, MTHF-20, MTHF-50
Gen IL28B: rs12979860 y rs8099917
Ref.: IL28-10, IL28-20, IL28-50